Throughout time, indigenous Latin cultures have been using the holy wood for cleansing, ceremonies, and rituals. Ancient shamans would use the sacred wood in healing ceremonies with the widely held belief that the tree carried spiritual healing energy, able to purify and clear negative energies and create a sacred space. Cleansing your environment with palo santo is much like praying, there really are no rules. There are best practices ( i.e. you should only go clockwise around your house, or you need to cleanse every doorway ) but ultimately this is your ritual - do what feels right for you.
Smoke cleansing Mantra: I now release and send all negative energy to the light